Table 1 Demographic data, pulmonary function test and SF-36 results of the study population
From: Effect of thyroid function on COPD exacerbation frequency: a preliminary study
| PARAMETERS | COPD + Hypothyroidism | COPD | CONTROL | P |
|---|---|---|---|---|
| Group 1 | Group 2 | Group 3 | ||
| (n = 44) | (n = 44) | (n = 40) | ||
| Age (years) | 64.1 ± 7.1 | 66.5 ± 6 | 64.7 ± 3.4 | 0.26 |
| Gender (F/M) | 22/22 | 22/22 | 20/20 | 1 |
| Height (cm) | 162.7 ± 7.2 | 166.2 ± 7.3 | 167 ± 8.4 | 0.11 |
| Weight (kg) | 78.7 ± 15.8 | 76.1 ± 17.1 | 78.5 ± 12.2 | 0.9 |
| BMI (kg/m2) | 29.73 ± 5.74 | 27.43 ± 5.35 | 27.88 ± 3.98 | 0.296 |
| Cigarette pack/year | 37.6 ± 22.6a,b | 54.2 ± 26.7a,c | 0bc | <0.0001 |
| FEV1/FVC | 67.2 ± 11.1a,b | 53.2 ± 15.6a,c | 79.5 ± 5.2b,c | <0.0001 |
| FEV1(L) | 2.1 ± 0.7a | 2.01 ± 0.53b | 3.6 ± 0.58 a,b | <0.0001 |
| FEV1(%) | 83.1 ± 22.2a | 77.5 ± 16.2b | 116.9 ± 17.5 a,b | <0.0001 |
| FVC (L) | 3.1 ± 0.9a,b | 3.67 ± 0.9a,c | 4.6 ± 0.8 b,c | <0.0001 |
| FVC (%) | 100.1 ± 19.2a | 108.9 ± 21b | 121.8 ± 19.6 a,b | 0.003 |
| FEF25–75 (%) | 47.5 ± 27.4a,b | 29.6 ± 12.3a,c | 95.1 ± 21.9 b,c | <0.0001 |
| TLC (%) | 107.2 ± 19.5 | 105.3 ± 19 | 113.9 ± 15.9 | 0.22 |
| TLC (L) | 5.9 ± 1.4 | 6.5 ± 1.5 | 6.55 ± 1.03 | 0.32 |
| MIP (cmH2O) | 69.6 ± 30.7 | 67.3 ± 17.5 | 74.05 ± 24.3 | 0.673 |
| MEP (cmH2O) | 25.6 ± 9.1a,b | 34.9 ± 11.5a,c | 26.7 ± 6.4b,c | 0.004 |
| General health | 35 (0–80)a | 45 (10–70)b | 69.5 (40–82)a,b | <0.0001 |
| Physical functioning | 52.5 (0–100) a | 62.5 (25–95) b | 90 (50–100) a,b | <0.0001 |
| Physical Role limitation | 25 (0–100) a | 25 (0–100) b | 100(50–100)a,b | <0.0001 |
| Emotional Role limitation | 33 (0–100) a | 33 (0–100) b | 66.6(0–100) a,b | <0.0001 |
| Social functioning | 50 (13–100) a | 56 (0–100) b | 87.5(38100)a,b | <0.0001 |
| Pain | 60 (0–100) a | 85 (20–100) b | 100(40–100)a,b | 0.029 |
| Vitality | 52.5 (10–85) a | 57.5 (20–92) b | 80.5(45100)a,b | 0.001 |
| Mental health | 52.5 (12–80) a | 58 (15–90) b | 72 (50–95) a,b | <0.0001 |